About NGS and how it works


The human genome is the genetic blueprint of the human body.  The traditional way of sequencing, also known as the Sanger method was too slow and costly to practically support the process of sequencing whole variety of genes.  

With technology boost, we are now able to get more than 1.8 terabases of data from single sequencing compared to one gigabase of data ten years ago.  As cost comes down but more data collected from single sequence, we will be able to see the gene differences and discover the critical genes that cause cancer and other diseases.


How is it done?


Genetic testing procedure involves 3 major steps.
















Step 1: Prepare DNA library sample using a target enrichment method.


Step 2: Sequence target genes using Next Generation Sequencing platform.


Step 3: Analyze the raw sequencing data using bioinformatics analysis tools.






(Step 1) Detail view of target enrichment assay process








(Step 2) Detail view of NGS sequencing run

(Step 3) Detail view of bioinformatics analysis